Clinical Registries and Biobanks
Overview
The Monash Public Health Biorepository houses biospecimens from a diverse range of studies undertaken by researchers from Monash University, including blood and urine specimens collected from Australian participants of the NIH/NHMRC-funded ASPREE (ASPirin in Reducing Events in the Elderly) clinical trial, and the post-trial cohort follow-up study, ASPREEE-XT.
Baseline and three-year and nine-year follow up biospecimens from ASPREE participants constitute the ASPREE Healthy Ageing Biobank and, together with clinical data from the participants, represent a unique global resource for genetic and biomarker discoveries in older Australians.
The biorepository also houses tumour tissue samples collected from ACES (ASPREE Cancer Endpoints Study), an ASPREE sub-study designed to look at the effect of low-dose aspirin on cancer, and stool samples being collected as part of the ASPREE-XT microbiome sub-study.
Access and contact
A/Prof Robyn Woods
Director, ASPREE
Robyn.Woods@monash.edu
aspree.org/aus/about-the-aspree-project/sub-studies/
Coordinated by Baker Heart and Diabetes Institute, the AusDiab study is the largest Australian longitudinal population-based study examining the natural history of diabetes, heart disease and kidney disease in Australians over 25 years of age.
The baseline study of 11,247 participants provided benchmark national data on the prevalence of diabetes, obesity, hypertension and kidney disease in Australia.
A new study, PREDICT, aims to develop ways of identifying those people with type 2 diabetes who are at risk of developing diabetes complications.
Access and contact
Researchers and potential collaborators wishing to access the AusDiab datasets or biological samples should contact www.baker.edu.au/impact/ausdiab and review the Data Access Protocol links.
Established in the 1990s, the Victorian HIV Blood and Tissue Storage Bank and clinical database is an initiative of the state-wide Victorian HIV Service at The Alfred and Burnet Institute.
It has prospectively stored leftover serum samples from requested HIV viral load tests for patients managed at The Alfred. The biobank is active and growing, and currently holds nearly 70,000 samples linked with relevant clinical information from close to 5,000 HIV patients.
It has the ability to track individual patients from naive to treatment suppressed, and also contains historical samples from before the widespread use of anti-retroviral therapy.
Access and contact
The biobank is available as a research tool.
Ms Janine Roney
Research Manager, Infectious Diseases Clinical Research Unit
Alfred Health
j.roney@alfred.org.au
Prof Jennifer Hoy
Director of HIV Medicine
Alfred Health
Jennifer.hoy@monash.edu
The Alfred Brain Tumour Bio-databank is a stored collection of biological samples and data from patients who have been diagnosed with a brain tumour. These samples and data are used for research purposes. The bio-databank improves precision in diagnosis, treatment and management of brain tumours.
www.alfredhealth.org.au/research/research-areas/alfred-brain-tumour-bio-databank
The Alfred Cancer Biobank is a collaborative platform. Established in late 2019 by Alfred Health and Monash University, our mission is to support innovative cancer research projects that aim to improve patient outcomes.
We do this by storing donated biospecimens (samples) from people who have been diagnosed with various cancers. These samples can then be used in targeted research aimed at improving cancer treatments and outcomes.
www.alfredhealth.org.au/research/research-areas/alfred-cancer-biobank
The Alfred Neuroscience Bio-databank (ANB) is a biorepository and databank that provides human tissue, saliva, urine, blood, and derivative products with coded clinical data that are used for research into neurological diseases.
https://www.alfredhealth.org.au/research/research-areas/ANB-Landing